PHARMACIAN PDRN 12000 CREAM
PDRN12000 cream: 12,000 ppm PDRN, stated on the pack
A daily Korean moisturizing cream with 12,000 ppm salmon DNA PDRN , a 15-peptide blend and ceramide NP. It gives lasting hydration, supports the moisture barrier and helps skin look smoother, firmer and more radiant.
Quick facts
| Key ingredient | Sodium DNA (salmon-derived PDRN), 12,000 ppm as labelled |
| Also labelled | Lactobacillus extracellular vesicles 5,580 ppm · yeast extracellular vesicles 5,580 ppm · allantoin 3,000 ppm |
| Supporting ingredients | Niacinamide, panthenol, ceramide NP, milk exosome, adenosine, 15 peptides |
| Size | 30 g (1.05 oz) |
| Skin type | All skin types |
| How to use | Take an appropriate amount and spread evenly over the face |
| Made in | Korea (WINOVA Co., Ltd.) |
Why PDRN?
PDRN (polydeoxyribonucleotide) is made of purified DNA fragments derived from salmon. In skincare it is a hydrating, skin-conditioning ingredient. It is also one of the fastest-growing ingredients in Korean skincare. What is PDRN? Read the full guide
Most PDRN skincare products don’t say how much PDRN they contain. PDRN12000 puts the number in its name. On the label it appears as sodium DNA , the ingredient name for PDRN derived from salmon DNA.
Topical PDRN vs injectable PDRN. PDRN treatments such as injections and skin boosters are done in clinics by a doctor. PDRN12000 is a cream for everyday home use. Its role is hydration, comfort and the look of healthier skin.
The formula
PDRN, 12,000 ppm
Salmon-derived sodium DNA to hydrate and help skin look smoother and more supple.
Peptide blend
15 peptides, including copper tripeptide-1, acetyl hexapeptide-8 and palmitoyl pentapeptide-4. They are included for smoother, firmer-looking skin.
Barrier support
Ceramide NP, panthenol and allantoin help keep skin comfortable and hydrated.
Even-looking tone
Niacinamide and adenosine round out the formula.
Extracellular vesicles
Lactobacillus and yeast extracellular vesicles (5,580 ppm each) and milk exosome, as listed on the label.
Texture and feel
A soft cream that spreads easily and absorbs without a sticky finish, so you can apply makeup straight after. It is comfortable enough for dry skin and light enough for combination skin. To confirm: CONFIRM texture description with product sample.
What to expect
With twice-daily use, most people notice first that skin feels more hydrated and comfortable. Over the following weeks, skin texture looks smoother, fine lines from dryness look softer, and skin looks more elastic and radiant. Results vary with skin type, routine and consistency.
How to use it in your routine
- Cleanse, then apply toner or serum.
- Take an appropriate amount of PDRN12000 and spread evenly over the face.
- Use morning and night. In the morning, finish with sunscreen.
Pairs well with: a hyaluronic acid serum underneath for extra hydration, and MELALESS 100,000 in the morning for a more even-looking tone, or NMN30000 at night if you want a richer cream. To confirm: CONFIRM pairing advice with brand.
Who it's for
- Skin that feels dry, tight or dehydrated , especially in air-conditioned rooms.
- Sensitive skin that needs a soothing, barrier-friendly cream (patch-test first).
- Anyone who wants a smoother, more radiant-looking complexion.
- People who prefer stated ingredient amounts over vague claims.
PDRN12000 FAQ
Do PDRN creams actually work?
A PDRN cream works as a well-formulated moisturizing cream. It hydrates, supports the skin barrier and helps skin look smoother and more radiant with regular use. It won’t give the results of a clinic treatment, and no cream should promise that.
Does PDRN12000 contain collagen?
No. Collagen isn’t on the ingredient list. The formula relies on PDRN, peptides, niacinamide and ceramide NP to help skin look firmer and smoother.
Do I also need a PDRN serum?
No. PDRN12000 works on its own. If you like layering, a hydrating serum underneath is enough.
What not to mix with PDRN cream?
There are no known conflicts with common skincare ingredients. If your skin is sensitive, don’t introduce several new actives (retinol, strong acids, vitamin C) in the same week.
Can I use PDRN cream during pregnancy?
Ask your doctor before starting any new skincare product during pregnancy or breastfeeding.
Is this the same as PDRN injections?
No. PDRN12000 is a cosmetic cream for daily use at home. PDRN injections and skin boosters are clinic treatments done by a doctor.
Does it smell of fish?
No. The PDRN is purified DNA fragments, not fish tissue.
Can I use it with vitamin C or retinol?
Usually, yes. If your skin is sensitive, apply them at different times of day.
Is it suitable for sensitive skin?
It is labelled for all skin types. Patch-test first, and stop use if irritation occurs.
How long does a 30 g tube last?
Full ingredient list
Water, dipropylene glycol, glycerin, butylene glycol, caprylyl methicone, 1,2-hexanediol, niacinamide, betaine, sodium DNA (12,000 ppm), hydrogenated polydecene, panthenol, cetearyl olivate, Lactobacillus extracellular vesicles (5,580 ppm), yeast extracellular vesicles (5,580 ppm), C14-22 alcohols, sorbitan olivate, whey filtrate, calcium aluminum borosilicate, allantoin (3,000 ppm), ammonium acryloyldimethyltaurate/VP copolymer, carbomer, caprylic/capric triglyceride, tromethamine, C12-20 alkyl glucoside, fucosyllactose, tocopheryl acetate, milk exosome, ethylhexylglycerin, adenosine, ceramide NP, phytosterols, oleic acid, hydrogenated lecithin, disodium EDTA, lemon peel oil, glyceryl stearate, bergamot oil, Candida bombicola/glucose/methyl rapeseedate ferment, polyglyceryl-10 laurate, cetearyl alcohol, litsea cubeba fruit oil, polyglyceryl-3 methylglucose distearate, stearic acid, amyris balsamifera bark oil, cardamom seed oil, juniperus virginiana oil, coconut oil, rice germ oil, propanediol, clary oil, Artemisia capillaris extract, thyme flower/leaf oil, olive extract, copper tripeptide-1, acetyl hexapeptide-8, acetyl tetrapeptide-2, acetyl tetrapeptide-5, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, tripeptide-1, acetyl tetrapeptide-3, hexapeptide-11, nonapeptide-1, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, tripeptide-32.
English INCI translated from the Korean label. To confirm: REPLACE with the INCI printed on the Malaysian pack before publishing.
Cautions: For external use only. Stop use and consult a doctor if redness, swelling or itching occurs, including after sun exposure. Do not apply to broken skin. Keep out of reach of children. Store away from direct sunlight.
Ready to try PDRN12000?
Questions about your skin type or routine first? Message us and a person will reply.
Cosmetic product. Individual results vary.